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Flagship Project
A1 - Cryo-EM Structures of Emerging Viruses
Cryo-EM analysis of a feline coronavirus spike protein reveals a unique structure and camouflaging glycans
Hsu
et al. PNAS
(2020)
117
(3)
1438-1446
.
A2 - Cryo-EM Structures of Cancer-Relevant Protein Complexes
Structural analysis of cancer related protein-phosphoprotein (or other PTM protein) complexes involving kinases and phosphatases.
Human DNA Polymerase μ Can Use a Noncanonical Mechanism for Multiple Mn
2+
-mediated Functions
Tsai & Wu
et al. J Am Chem Soc.
(2019)
141
(21)
8489-8502
.
A3 - Structure-Based Rapid Epitope Mapping for Antibody Drugs
Structural approach for high throughput epitope mapping for antibody drugs and disease-relevant antibodies.
Dr. An-Suei Yang's group (2020)
High throughput cytotoxicityscreening of anti-HER2 immunotoxins conjugated with antibody fragments from phagedisplayed synthetic antibody libraries
Yang & Wang
et al. Scientific Reports
(2016)
6 31878
Structural basis for the antibody neutralization of Herpes simplex virus
Wang
et al. Acta Cryst.
(2013)
D69, 1935–1945
Contact: Ms. Ming-Yi Lin Email:
mylin@gate.sinica.edu.tw
No. 128 Academia Road, Section 2, Nankang, Taipei 11529, Taiwan Tel : 886-2-27855696 #3040
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